tributyrin
A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines.
| Synonym: | butyryl triglyceride glyceryl tributyrate |
|---|---|
| Abbreviation: | TB |
| Chemical structure: | 1,2,3-propanetriyl butanoate 1,2,3-tributyrylglycerol butanoic acid 1,2,3-propanetriyl ester |
| IND number: | 47776 |
| NSC code: | 661583 |