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vopikitug

A monoclonal antibody against CD25 (IL-2R alpha), with potential antineoplastic activity. Upon administration, vopikitug targets and binds to CD25 expressed on tumor-infiltrating regulatory T (Treg) cells. This may deplete Treg cells and prevent immunosuppression, thereby enhancing anti-tumor immune responses. CD25, the alpha chain of the interleukin (IL)-2 receptor, is highly expressed on Treg cells but not on effector T (Teff) cells in tumors.
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Synonym:anti-CD25 monoclonal antibody RG6292
anti-CD25 monoclonal antibody RO7296682
T-regulatory cell-depleting antibody RO7296682
Code name:RG 6292
RG-6292
RG6292
RO 7296682
RO-7296682
RO7296682
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