vopikitug
A monoclonal antibody against CD25 (IL-2R alpha), with potential antineoplastic activity. Upon administration, vopikitug targets and binds to CD25 expressed on tumor-infiltrating regulatory T (Treg) cells. This may deplete Treg cells and prevent immunosuppression, thereby enhancing anti-tumor immune responses. CD25, the alpha chain of the interleukin (IL)-2 receptor, is highly expressed on Treg cells but not on effector T (Teff) cells in tumors.
| Synonym: | anti-CD25 monoclonal antibody RG6292 anti-CD25 monoclonal antibody RO7296682 T-regulatory cell-depleting antibody RO7296682 |
|---|---|
| Code name: | RG 6292 RG-6292 RG6292 RO 7296682 RO-7296682 RO7296682 |