Skip to main content
An official website of the United States government
NIH Websites Are Changing
Per Executive Order 14434, federal agencies are now using "Super Intelligence" (SI) in place of "Artificial Intelligence" (AI). You may see both terms across NIH content during this transition.

yttrium Y 90 anti-CD45 monoclonal antibody BC8

A radioimmunoconjugate containing the murine IgG1 anti-CD45 monoclonal antibody (MoAb) BC8 labeled with yttrium 90 (Y90), with potential immunotherapeutic activity. Yttrium Y 90 anti-CD45 monoclonal antibody BC8 binds to CD45 antigen, a receptor protein-tyrosine phosphatase expressed on the surface of both normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.
Check for active clinical trials using this agentView this agent in the NCI Thesaurus
Abbreviation:90Y anti-CD45 MAb BC8
90Y anti-CD45 MoAb BC8
Search NCI's Drug Dictionary
Please enter up to 30 characters for your search