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zidovudine

A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines.

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Synonym:	azidothymidine
US brand name:	Retrovir
Foreign brand name:	Aztec
Abbreviation:	AZT ZDV
Code name:	BW-A509U
Chemical structure:	3'-azido-3'-deoxythymidine
IND number:	26635 30858 33134 34545 35782
NSC code:	602670

zidovudine

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