zileuton
A synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma.
| US brand name: | Zyflo |
|---|---|
| Abbreviation: | ZLT |
| Chemical structure: | (+-)-N-Hydroxy-N-(1-benzo[b]thien-2-ylethyl)-urea N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea |