zinpentraxin alfa
A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, zinpentraxin alfa may inhibit myofibroblast generation by preventing the differentiation of circulating monocytes into fibrocytes and profibrotic macrophages. PTX2 is a circulating plasma protein that belongs to the class of pattern recognition receptors (PRR) of the innate immune system.
Synonym: | pentraxin 2 PRM-151/PTX2 recombinant human pentraxin 2 recombinant human PTX2 recombinant human serum amyloid P |
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Code name: | PRM-151 PRM151 |