zorubicin hydrochloride
A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
| Synonym: | benzoyl hydrazone daunorubicin daunorubicin benzoylhydrazone hydrochloride rubidazone |
|---|---|
| Foreign brand name: | Zorubicine |
| Abbreviation: | RBZ |
| Code name: | RP-22050 |
| Chemical structure: | (2S-cis)-benzoic acid[1-[4-[3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide benzoic acid hydrazide 3-hydrazone with daunorubicin |
| IND number: | 12942 |
| NSC code: | 164011 |