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zorubicin hydrochloride

A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
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Synonym:benzoyl hydrazone daunorubicin
daunorubicin benzoylhydrazone hydrochloride
rubidazone
Foreign brand name:Zorubicine
Abbreviation:RBZ
Code name:RP-22050
Chemical structure:(2S-cis)-benzoic acid[1-[4-[3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3-naphthacenyl]ethylidene]hydrazide
benzoic acid hydrazide 3-hydrazone with daunorubicin
IND number:12942
NSC code:164011
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