golnerminogene pradenovec
A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF.
| Synonym: | adenovirus 5-tumor necrosis factor alpha AdGV11-TNFalpha tumor necrosis factor adenovirus 5 vector |
|---|---|
| US brand name: | TNFerade |
| Abbreviation: | Ad 5-TNF Alpha Ad5-TNFa |
| Code name: | ADgv EGR.TNF.11D |