NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

golnerminogene pradenovec
A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:adenovirus 5-tumor necrosis factor alpha
tumor necrosis factor adenovirus 5 vector
US brand name:TNFerade
Abbreviation:Ad 5-TNF Alpha
Code name:ADgv EGR.TNF.11D