atrasentan hydrochloride
The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
| US brand name: | Xinlay |
|---|---|
| Code name: | (+)-A 127722 ABT 627 ABT-627 |
| Chemical structure: | (2R,3R,4S)-4-(1,3-benzodioxo-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid monohydrochloride |
| NSC code: | 720763 |