As a result of the current Federal government funding situation, the information on this website may not be up to date or acted upon.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit https://cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at https://www.opm.gov.

NCI Drug Dictionary

  • Resize font
  • Print
  • Email
  • Facebook
  • Twitter
  • Google+
  • Pinterest

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

Browse:
imiquimod
Patient Information
A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Check for active clinical trials using this agent. (NCI Thesaurus)

US brand name:Aldara
Abbreviation:IMQ
Code name:R 837
S 26308
Chemical structure:
  • 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-
  • 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline