azaserine
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent.
| Synonym: | diazoacetate (ester) L-Serine diazoacetic acid ester with serine diazoacetylserine L-azaserine serine diazoacetate |
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| Abbreviation: | AZS |
| Code name: | CL-337 CN-15757 P-165 |
| Chemical structure: | L-diazoacetate (ester) serine L-serine diazoacetate (ester) O-diazoacetyl-L-serine |