NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A synthetic triazine analogue of uridine with antimetabolite activity. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di-, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym: 6-azauracil riboside
Abbreviation: 6-AZUR Chemical structure:
- 1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl
- 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine riboside