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NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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therapeutic estradiol
A steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Typically esterified, estradiol derivatives are formulated for oral or parenteral administration. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. Estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:17 beta-estradiol
Estraldine
US brand name:Aquadiol
Estrace
Vagifem
Vivelle
Foreign brand name:Dimenformon
Diogyn
Diogynets
Ovocylin
Progynon
Abbreviation:ESDL
Chemical structure:(17beta)-estra-1,3,5(10)-triene-3,17-diol