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beclomethasone dipropionate

The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
US brand name:Beclovent
Beconase
Qnasl
Qvar
Vancenase
Vanceril
Code name:SCH-18020W
Chemical structure:(11beta,16beta)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione dipropionate
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