methylmercaptopurine riboside
A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation.
| Synonym: | methylthioinosine |
|---|---|
| Abbreviation: | 6-MMPR MMPR |
| Code name: | NCI-C04784 SQ 21977 |
| Chemical structure: | 6-(methylmercapto)purine ribonucleoside 6-(methylthio) inosine 6-(methylthio)purine ribonucleoside 6-(methylthio)purine riboside 6-methyl MP riboside 6-methylmercaptopurine riboside 6-methylthioinosine 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI) 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate 9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl beta-D-ribosyl-6-methylthiopurine purine-6-thiol,6-methyl-9-ribofuranosyl |
| IND number: | 19524 2818 924 |
| NSC code: | 40774 |