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idarubicin hydrochloride

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The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds
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Synonym:4-demethoxydaunomycin
idarubicin HCl
US brand name:Idamycin
Idamycin PFS
Foreign brand name:Zavedos
Code name:IMI-30
SC-33428
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