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goserelin acetate

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The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production.
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US brand name:Zoladex
Abbreviation:ZDX
Chemical structure:D-Ser(bu(t))(6)azgly(10)-LHRH acetate
NSC code:606864
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