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sodium salicylate

The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells.
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Synonym:salicylate, sodium
Chemical structure:benzoic acid, 2-hydroxy-, monosodium salt
NSC code:202167
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