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deferasirox

A synthetic, orally bioavailable, achiral, tridentate triazole derived from salicylic acid with iron-chelating activity. Deferasirox chelates iron at a 2:1 (ligand:iron) ratio. Because of its oral availablity,and long plasma half-life, this agent may be superior to desferrioxamine (desferal, DFO), which is orally inactive and has a short plasma half-life.
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US brand name:Exjade
Jadenu
Chemical structure:4-(3,5-bis-(hydroxy-phenyl)-1,2,4-triazol-1-yl)-benzoic acid
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