NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- vascular endothelial growth factor antisense oligonucleotide
An antisense oligonucleotide with potential antiangiogenesis activity. Vascular endothelial growth factor (VEGF) antisense oligonucleotide binds directly to binds VEGF A/C/D mRNA, leading to mRNA degradation and the inhibition of VEGF A-mediated angiogenesis and VEGF C/D-mediated lymphangiogenesis. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym: VEGF antisense oligonucleotide US brand name: Veglin Abbreviation: VEGF-AS