NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- recombinant human papillomavirus quadrivalent vaccine
A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified
virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity. The immunoprohylactic efficacy of L1 VLP vaccines, such as recombinant human papillomavirus quadrivalent vaccine, appear to be mediated by the development of humoral immune
responses. HPV Types 16 and 18 account for approximately 70% of cervical cancers and HPV Types 6 and 11 account for approximately 90% of genital warts. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym: quadrivalent HPV (type 6, 11, 16 and 18) L1 virus-like particle vaccine US brand name: Gardasil