NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A synthetic chlorophenyl-butanoic acid derivative with muscle relaxant activity. Baclofen acts as a gamma-aminobutyric acid (GABA) agonist specific for GABA-B receptors in the central nervous system (CNS). At spinal and supraspinal sites, this agent reduces excitatory transmission. Check for active clinical trials using this agent. (NCI Thesaurus)
US brand name: Lioresal Code name: BA34647 Chemical structure:
- 4-Amino-3-(4-chlorophenyl)-butanoic Acid
- beta-(Aminomethyl)-4-chlorobenzenepropanoic acid