Skip to main content

Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

dianhydrogalactitol

A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest.

Check for active clinical trials using this agent View this agent in the NCI Thesaurus

Synonym:	bi-functional alkylating agent VAL-083 dianhydrodulcitol diepoxydulcitol diepoxygalactitol dulcitol diepoxide galactitol
Abbreviation:	DAG
Code name:	VAL-083 VAL083
Chemical structure:	1,2,5,6 dianhydrogalactitol 1,2:5, 6-diepoxydulcitol 1,2:5,6 dianhydrogalactitol 1,2:5,6-dianhydrodulcitol galactitol, 1,2:5,6-dianhydro- (8CI 9CI)

dianhydrogalactitol

Search NCI's Drug Dictionary