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LMB-7 immunotoxin

A single chain chimeric protein consisting of a monoclonal antibody fragment attached to a portion of the Pseudomonas exotoxin A. LMB-7 immunotoxin attaches to B3, a Lewis Y-related carbohydrate epitope on some solid tumor cells. The antibody attaches to the cell and the exotoxin inhibits protein synthesis by inactivating elongation factor 2.

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Synonym:	B3(Fv)-PE38 B3(Fv)-PE38 Immunotoxin HB21(Fv)PE40 immunotoxin LMB-7 LMB-7 (Single-Chain Immunotoxin)
IND number:	5863
NSC code:	658931 659639

LMB-7 immunotoxin

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