Colorectal Cancer—Health Professional Version
Colorectal cancer studies often consider colon and rectal cancer together. Worldwide, colorectal cancer is the third most common form of cancer. Find evidence-based information on colon and rectal cancer treatment, causes and prevention, screening, research, genetics, and statistics.
Colorectal Cancer Treatment
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Colon Cancer Treatment (PDQ®)
Colon cancer treatment can include open surgical resection for localized disease, chemotherapy, targeted therapy, radiation, and local ablation. Get detailed information about colon cancer treatment in this clinician summary.
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Rectal Cancer Treatment (PDQ®)
Rectal cancer treatment options can include surgery, radiation therapy, chemoradiation, chemotherapy, targeted therapy, ablation, and surveillance. Get detailed information about colon cancer treatment in this clinician summary.
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Childhood Colorectal Cancer Treatment (PDQ®)
This summary for clinicians discusses the clinical presentation, diagnostic evaluation, molecular features, outcomes, and treatment of pediatric colorectal cancer.
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Late Effects of Treatment for Childhood Cancer (PDQ®)
Late effects of cancer treatment can cause serious, life-threatening chronic health conditions that adversely affect the health of aging childhood cancer survivors. Get information about these late effects of pediatric cancer treatment.
Additional Colorectal Cancer Treatment Resources
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Drugs Approved for Colon and Rectal Cancer
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for colon and rectal cancers. The list includes generic names and brand names.
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Treatment Clinical Trials for Colon Cancer
Find a list of colon cancer treatment trials and use the filters to refine the results.
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Treatment Clinical Trials for Rectal Cancer
Find a list of rectal cancer treatment clinical trials and use the filters to refine the results.
Prevention of Colorectal Cancer
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Colorectal Cancer Prevention (PDQ®)
Get detailed information about risk factors for colorectal cancer and potential interventions for prevention in this summary for clinicians.
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Colorectal Cancer Risk Assessment Tool
An interactive calculator, designed by scientists at the National Cancer Institute, that estimates a patient's risk of developing colorectal cancer (colon or rectal).
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Prevention Clinical Trials for Colon Cancer
Find a list of colon cancer prevention clinical trials.
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Prevention Clinical Trials for Rectal Cancer
Find a list of rectal cancer prevention clinical trials.
Genetics Information
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Genetics of Colorectal Cancer (PDQ®)
Hereditary colorectal cancer syndromes include Lynch syndrome and several polyposis syndromes. Learn about the genetics, clinical manifestations, management, and psychosocial aspects of these and other hereditary colon cancer syndromes.
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MBD4-Associated Neoplasia Syndrome (PDQ®)
MBD4-Associated Neoplasia Syndrome is a hereditary cancer syndrome associated with the MBD4 gene. Learn about MBD4-Associated Neoplasia Syndrome’s clinical features and management.
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Cancer Genetics Risk Assessment and Counseling (PDQ®)
Cancer genetics risk assessment and genetic counseling includes family history, psychosocial assessments, and education on hereditary cancer syndromes, testing, and risk. Get more information including the ethical, legal, and social implications of geneti
Screening for Colorectal Cancer
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Colorectal Cancer Screening (PDQ®)
Get detailed information about colorectal cancer screening tests, such as fecal occult blood test, sigmoidoscopy, colonoscopy, stool DNA, and more. Find potential benefits and harms of these screening tests in this summary for clinicians.
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Tests to Detect Colorectal Cancer and Polyps
A fact sheet that discusses the tests used to screen people for colorectal cancer and key features of the different tests to consider when choosing one.
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Screening Clinical Trials for Colorectal Cancer
Find a list of colorectal cancer screening clinical trials and use the filters to refine the results.