Causes and Prevention Research
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Air Is Life: The Navajo Nation’s Historic Commercial Tobacco BanPosted:
With the passage of the Air is Life Act of 2021, the Navajo Nation enacted the most comprehensive ban on commercial tobacco products of any American Indian tribe to date.
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FDA Oversight of E-Cigarettes Gathers Speed: A Conversation with Mitch ZellerPosted:
Companies that want to market e-cigarettes in the United States must now submit applications to the Food and Drug Administration (FDA). In this interview, Mitch Zeller, director of FDA’s Center for Tobacco Products, provides insights into FDA actions on e-cigarettes.
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Despite Proven Safety of HPV Vaccines, More Parents Have ConcernsPosted:
Despite consistent evidence that HPV vaccines are safe and effective, a new study shows that more parents are citing concerns about their safety. Researchers cautioned that efforts are needed to counter this trend and improve vaccination rates.
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Alcohol Tied to 750,000 Cancer Cases Worldwide in 2020Posted:
Nearly 750,000 cases of cancer diagnosed worldwide in 2020, or 4%, can be attributed to alcohol consumption, according to a new study. While heavy drinking accounted for most cases, light and moderate drinking accounted for a modest amount.
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Advancing Cancer Prevention: A Conversation with NCI’s Dr. Philip CastlePosted:
The director of NCI’s Division of Cancer Prevention, Dr. Philip Castle, discusses the division’s priority areas and his vision for making more rapid progress in cancer prevention, including moving toward precision prevention and immunoprevention.
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International Research Teams Explore Genetic Effects of Chernobyl RadiationPosted:
One study examined whether genetic changes associated with exposure to radiation from the 1986 accident were passed from parent to child. A second study documented the genetic changes in thyroid tumors from people exposed as children or fetuses to radiation from the accident.
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NF1 Associated with More Cancer Types Than Previously KnownPosted:
The study also found that people with neurofibromatosis type 1 (NF1) developed some cancers at an earlier age and were more likely to die from several cancer types, which make preventive measures and early diagnosis important for people with NF1.
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Persistent Poverty Linked to Increased Risk of Dying from CancerPosted:
People who live in counties in the United States with persistent poverty are more likely to die from cancer than people in other counties, a new study shows, highlighting the influence of social and structural factors on health.
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Smoking Initiation Shifting from Teens to Young AdultsPosted:
The age at which people tend to start smoking has shifted upwards, with more young adults than teens trying smoking for the first time or becoming regular smokers, according to a new study.
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Can Taking Aspirin Help Prevent Cancer?Updated:
Even as a federal advisory panel has supported the use of aspirin to reduce the risk of colorectal cancer in some people, researchers are investigating how aspirin works against cancer and whether it may help reduce the risk of other cancers.
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Regular Aspirin Use May Increase Older People’s Risk of Dying from CancerPosted:
Regular use of low-dose aspirin may increase an older person’s risk of being diagnosed with advanced cancer and of dying from cancer, results from the ASPREE clinical trial suggest. Learn more about what this 19,000-participant study found.
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Updated Nutrition Facts Label Reflects Science on Diet and Health, including CancerPosted:
On January 1, 2020, the Food and Drug Administration (FDA) began requiring food manufacturers to display updated nutrition facts labels on their product packaging. Experts from FDA and NCI discuss the update and the research that underpins the changes.
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Single Dose of HPV Vaccine Yields Long-Term Protection from Many Cancer-Causing TypesPosted:
More than a decade after vaccination, women who had received a single dose of the HPV vaccine continued to be protected against infection with the two cancer-causing HPV types targeted by the vaccine, an NCI-funded clinical trial shows.
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Pediatricians’ Offices Can Help Parents Quit Smoking, Study ShowsPosted:
Researchers tested a program that trains pediatricians’ offices to provide smoking cessation treatment to parents during visits with their child’s doctor. The approach is intended to reach adults who are motivated to quit to protect their child’s health.
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NCI Study Finds Long-term Increased Risk of Cancer Death Following Common Treatment for HyperthyroidismPosted:
Findings from a new NCI study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer.
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UK Clinical Trial Compares E-cigarettes, Nicotine-Replacement Products for Smoking CessationPosted:
Researchers in the United Kingdom have found that e-cigarettes combined with counseling may be more helpful to smokers trying to quit tobacco than counseling and nicotine-replacement products, such as patches, gums, and lozenges.
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BRCA Exchange Aggregates Data on Thousands of BRCA Variants to Inform Understanding of Cancer RiskPosted:
The BRCA Exchange, a global resource that includes data on thousands of inherited variants in the BRCA1/BRCA2 genes, is available to the public through a website and new smartphone app.
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Study Finds Elevated Risk of Certain Rare Blood Cancers after Chemotherapy for Most Solid TumorsPosted:
In a new study, NIH investigators found that patients treated with chemotherapy for most solid tumors had an increased risk of tMDS/AML, a rare but often fatal blood cancer. The study, which used population-based data, was published in JAMA Oncology.
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Vitamin D Supplements Don’t Reduce Cancer Incidence, Trial ShowsPosted:
In the largest-ever randomized trial testing vitamin D for cancer prevention, the supplement did not lower the risk of developing cancer. The Vitamin D and Omega-3 Trial (VITAL) includes a nationally representative sample of nearly 26,000 participants.
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Eight Factors May Link Disparities in Cancer Death Rates and IncomePosted:
Eight factors may explain more than 80% of the relationship between poverty and disparities in cancer death rates at the county level, according to a new study. The largest mediator was a surprise to the researchers.
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Studying “Total Diet” and Its Impact on Health, Including Cancer RiskPosted:
Researchers are shifting how they assess diet and cancer risk, looking beyond the impact of individual foods or nutrients on health, and taking a more holistic approach, considering dietary patterns across the lifespan.
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Vaping Pods Produce High Nicotine Levels in Young UsersPosted:
Adolescents who use pod-style e-cigarettes had higher levels of nicotine in their bodies than is typically found in adolescents who smoke conventional cigarettes, a new study has found. The study's findings are concerning for several reasons.
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Cancer Prevention Message Is Key for HPV Vaccination Discussions with ParentsPosted:
Health care providers should emphasize cancer prevention when discussing HPV vaccination with the parents of preteens who are due to receive the vaccine, results from a new study show.
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HPV Vaccination Linked to Decreased Oral HPV InfectionsPosted:
A study of more than 2,600 young adults found that the prevalence of oral infection with four HPV types, including two cancer-causing types, was 88% lower in those who reported receiving at least one dose of an HPV vaccine than in those not vaccinated.
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U.S. Cancer Mortality Rates Falling, But Some Regions Left Behind, Study FindsPosted:
A study of nationwide mortality data found that, while cancer deaths in the U.S. dropped between 1980 and 2014, disparities persisted, and in 160 counties cancer mortality rose substantially.
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Shifts Seen in Tobacco Product Types Purchased in USPosted:
The consumption of cigarettes, small cigars, and chewing tobacco has declined over the past 15 years, according to a new study. These declines were partially offset by a rise in consumption of large cigars, pipe tobacco, and snuff.
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No Safe Level of Smoking: Even low-intensity smokers are at increased risk of earlier deathPosted:
People who consistently smoked an average of less than one cigarette per day over their lifetimes had a 64 percent higher risk of earlier death than people who never smoked.
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CDC Updates Recommendations on HPV VaccinePosted:
Updated CDC recommendations advise those younger than age 15 need only two doses of the HPV vaccine instead of three.
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Adolescents Who Wouldn’t Have Smoked May Be Drawn to E-CigarettesPosted:
The findings from a recent study suggest that adolescents are not just using e-cigarettes as a substitute for conventional cigarettes but that e-cigarettes are attracting new users to tobacco products.
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Setting the Stage for the Next Decade of Tobacco Control ResearchPosted:
A new report from an NCI working group lays out recommended priorities to help shape the institute’s future tobacco control research portfolio.
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Increased Physical Activity Associated with Lower Risk of 13 Types of CancerPosted:
A new study of the relationship between physical activity and cancer has shown that greater levels of leisure-time physical activity were associated with a lower risk of developing 13 different types of cancer; the risk of developing seven cancer types was 20 percent lower among the most active participants as compared with the least active participants.
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Improving Public Health through Increased Tobacco RegulationPosted:
NCI’s Dr. Robert Croyle discusses the Food and Drug Administration’s release of a rule that extends its regulatory authority over tobacco products to include cigars, e-cigarettes, hookah (waterpipe) tobacco.
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HPV Infections Targeted by Vaccine Decrease in U.S.Posted:
Infection with human papillomavirus (HPV) types targeted by the quadrivalent HPV vaccine has declined by nearly two-thirds among teenage girls since HPV vaccination was recommended in the United States.
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Mouse Study Points to Mechanism Linking Obesity and Colorectal Cancer RiskPosted:
A missing hormone in obese mice may help explain a longstanding association between obesity and an increased risk of colorectal cancer in humans.