This page contains brief information about dabrafenib mesylate and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
- Anaplastic thyroid cancer that is locally advanced or has spread to other parts of the body and cannot be treated with local therapy. It is used with trametinib dimethyl sulfoxide.
- Glioma that is low grade in children aged 1 year and older who require systemic therapy. It is used with trametinib dimethyl sulfoxide.
- Melanoma. It is used:
- With trametinib dimethyl sulfoxide in patients who have had surgery to remove cancer that has spread to the lymph nodes.
- Alone or with trametinib dimethyl sulfoxide in patients whose cancer cannot be removed by surgery or has spread to other parts of the body.
- Non-small cell lung cancer that has metastasized. It is used with trametinib dimethyl sulfoxide.
- Solid tumors. It is used with trametinib dimethyl sulfoxide in adults and children aged 6 years and older whose tumors cannot be removed by surgery or have spread to other parts of the body and have gotten worse after other treatment and cannot be treated with other therapies.¹
Dabrafenib mesylate is also being studied in the treatment of other types of cancer.
More About Dabrafenib Mesylate
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Dabrafenib Mesylate - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Dabrafenib Mesylate - Check for trials from NCI's list of cancer clinical trials now accepting patients.