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This combination contains the chemotherapy drugs cyclophosphamide, vincristine sulfate, doxorubicin hydrochloride (Adriamycin), methotrexate, and cytarabine and the steroid hormone dexamethasone. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the hyper-CVAD combination:
C = Cyclophosphamide
V = Vincristine Sulfate
A = Doxorubicin Hydrochloride (Adriamycin)
D = Dexamethasone

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

Hyper-CVAD with methotrexate and cytarabine is used to treat:

Hyper-CVAD is given as hyperfractionated therapy, in which the total daily dose is divided into smaller doses and given more than once a day.

This combination may also be used with other drugs or treatments or to treat other types of cancer.

More About Hyper-CVAD

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

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