Obligations by Budget Mechanism and Division

All NIH Institutes and Centers report their actual obligations each fiscal year by budget mechanism. The tables below organize NCI funding by mechanism and division. The number of awards, trainees, or employees for each mechanism, as well as the dollar amount and percent share of the total NCI budget for each funding mechanism is also included.

NCI Obligations by Mechanism

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The mechanism "Other Research" includes the following grants: Career Programs (K Awards), Cancer Education, Clinical Cooperative Groups, Pre-Doc Post-Doc Transition Awards, Education Projects-Cooperative Agreements, Minority Biomedical Research Support, Research Pathway in Residency, Pilot Research Project, Resource Grants, International Research Training Grants, Cooperative Conference Agreements, Conference Grants, and Other Transaction Authority (OTA).

NCI Obligations by Mechanism, FY 2025
*(Whole Dollars)*
Type of Mechanism	Mechanism	Number	Amount	% of Total Amount
Research Project Grants (RPGs)	Non-Competing	4,211	2,534,946,465	35.1%
	Administrative Supplements	346	46,645,802	0.6%
	Competing	964	651,504,958	9.0%
	Subtotal, without Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR)	5,175	3,233,097,225	44.8%
	SBIR/STTR Grants	226	181,570,134	2.5%
	Subtotal, RPGs	5,401	3,414,667,359	47.3%
Centers & SPOREs	Cancer Centers Grants-P20/P30	78	346,522,441	4.8%
	Specialized Programs of Research Excellence (SPORE)	58	119,314,520	1.7%
	Other P50s/P20s	0	5,445,316	0.1%
	Other Specialized Centers	90	135,793,355	1.9%
	Subtotal, Centers	226	607,075,632	8.4%
Other Research	Career Program
	Post-Doc Fellow Awards-K00	80	7,927,586	0.1%
	Research Scientist Development Award-K01	34	5,459,615	0.1%
	Academic/Teacher Award-K07	0	0	0.0%
	Clinical Investigator Award-K08	225	52,509,965	0.7%
	Physician Scientist Award (Program)-K12	26	17,127,656	0.2%
	Transitional Career Development-K22	48	8,907,559	0.1%
	Mentored Quantitative Research Career Development Award-K25	5	898,485	0.0%
	Early Stage Mentored Research and Career Development-K38	3	313,005	0.0%
	International Research Career Development Award-K43	2	341,457	0.0%
	Career Transition Award-K99	96	13,210,377	0.2%
	Subtotal, Career Program	519	106,695,705	1.5%
	Cancer Education Program-R25 (including BD2K)	92	25,863,349	0.4%
	Clinical Cooperative Groups-U10/UG1	25	307,754,018	4.3%
	Pre-Doc Post-Doc Transition Awards-F99	35	1,561,346	0.0%
	UE5 Education Projects	1	57,135	0.0%
	Minority Biomedical Support-S06	0	1,274,760	0.0%
	Research Pathway in Residency (R38)	2	961,159	0.0%
	Other Transaction Authority-OT2	36	40,922,249	0.6%
	Resource Grants-R24/U24/U2C	94	126,155,016	1.7%
	Cooperative Conference Agreements-U13/R13	30	826,609	0.0%
	International Research Training Grants-D43	8	2,943,896	0.0%
	International Training Cooperative Agreement (U2R)	0	700,000	0.0%
	Subtotal, Career and Other Research Grants	842	615,715,242	8.5%
	Subtotal, Research Grants	6,469	4,637,458,233	64.2%
National Research Service Award (NRSA) Fellowships	Trainees	607	80,642,468	1.1%
R&D Contracts	R&D Contracts	305	633,472,430	8.8%
	SBIR Contracts	19	14,212,371	0.2%
	NIH Management Fund/Service Supply Fund (SSF) Assessment	0	71,094,961	1.0%
	Subtotal, Contracts	324	718,779,762	10.0%
Intramural Research	Program	1,832	951,349,585	13.2%
	NIH Management Fund/SSF Assessment	0	310,781,833	4.3%
	Subtotal, Intramural Research	1,832	1,262,131,418	17.5%
Research Management & Support (RMS)	Research Management and Support (RMS)	1,287	363,295,917	5.0%
	SBIR RMS	0	4,772,653	0.1%
	NIH Management Fund/SSF Assessment	0	123,899,613	1.7%
	Subtotal, RMS	1,287	491,968,183	6.8%
Buildings and Facilities		0	30,000,000	0.4%
*Total NCI	(FTEs)	3,119	7,220,980,064	100%
All items in italics are non-add entries.

Division Obligations by Mechanism

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Total Division Obligations, FY 2025
*(Whole Dollars)*
Division	Total
Center for Cancer Research (CCR)	$608,345,982
Division of Cancer Epidemiology and Genetics (DCEG)	$85,375,184
Division of Cancer Treatment and Diagnosis (DCTD)	$560,009,769
Division of Cancer Biology (DCB)	$73,204,072
Division of Cancer Control and Population Sciences (DCCPS)	$138,762,137
Division of Cancer Prevention (DCP)	$230,050,309
Division of Extramural Activities (DEA)	$19,700,903
Office of the Director (OD)	$1,517,715,468
*Total Division	$6,532,479,204

Center for Cancer Research (CCR)

CCR Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Intramural Research	Program	$608,345,982
Intramural Research	NIH Management Fund/SSF Assessment	$0
*Total CCR		$608,345,982

Division of Cancer Epidemiology and Genetics (DCEG)

DCEG Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
R&D Contracts	R&D Contracts	$9,172,556
R&D Contracts	SBIR Contracts	$0
Intramural Research	NIH Management Fund/SSF Assessment Program	$0
Intramural Research	Program	$76,202,628
*Total DCEG		$85,375,184

Division of Cancer Treatment and Diagnosis (DCTD)

DCTD Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Centers & SPOREs	Cancer Centers Grants-P20/P30	$0
	SPOREs-P50	$118,961,554
	Other P50s/P20s	$0
	Other Specialized Centers	$28,802,338
	Subtotal, Centers	$147,763,892
Other Research Grants	Cancer Education Program-R25 (including BD2K)	$0
	Education Projects-UE5	$0
	Clinical Cooperative Groups-U10/UG1	$145,271,626
	Pre-Doc Post-Doc Transition Awards-F99	$0
	Minority Biomedical Support-S06	$0
	Research Pathway in Residency-R38	$0
	Pilot Research Project-OT2	$0
	Resource Grants-R24/U24/U2C	$0
	Cooperative Conference Agreements-U13/R13	$0
	International Research Training Grants-D43/U2R	$0
	Subtotal, Other Research Grants	$145,271,626
Subtotal, Research Grants		$293,035,518
R&D Contracts	R&D Contracts	$202,610,437
	SBIR Contracts	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, Contracts	$202,610,437
Research Management & Support (RMS)	RMS	$64,363,814
	SBIR RMS	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, RMS	$64,363,814
*Total DCTD		$560,009,769

Division of Cancer Biology (DCB)

DCB Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Centers & SPOREs	Cancer Centers Grants-P20/P30	$0
	SPOREs-P50	$0
	Other P50s/P20s	$420,965
	Other Specialized Centers	$41,563,651
	Subtotal, Centers	$41,984,616
Other Research Grants	Subtotal, Other Research Grants	$0
Subtotal, Research Grants		$41,984,616
R&D Contracts	R&D Contracts	$0
	SBIR Contracts	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, Contracts	$0
Research Management & Support (RMS)	RMS	$31,219,456
	SBIR RMS	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, RMS	$31,219,456
*Total DCB		$73,204,072

Division of Cancer Control and Population Sciences (DCCPS)

DCCPS Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Centers & SPOREs	Cancer Centers Grants-P20/P30	$0
	SPOREs-P50	$0
	Other P50s/P20s	$4,690,910
	Other Specialized Centers	$11,776,028
	Subtotal, Centers	$16,466,938
Other Research	Cancer Education Program-R25 (including BD2K)	$0
	Education Projects-UE5	$0
	Clinical Cooperative Groups-U10/UG1	$0
	Pre-Doc Post-Doc Transition Awards-F99	$0
	Minority Biomedical Support-S06	$0
	Research Pathway in Residency-R38	$0
	Pilot Research Project-OT2	$0
	Resource Grants-R24/U24/U2C	$0
	Cooperative Conference Agreements-U13/R13	$0
	International Research Training Grants-D43/U2R	$0
	Subtotal, Other Research Grants	$0
Subtotal, Research Grants		$16,466,938
R&D Contracts	R&D Contracts	$80,274,026
	SBIR Contracts	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, Contracts	$80,274,026
Research Management & Support (RMS)	RMS	$42,021,173
	SBIR RMS	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, RMS	$42,021,173
*Total DCCPS		$138,762,137

Division of Cancer Prevention (DCP)

DCP Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Centers & SPOREs	Cancer Centers Grants-P20/P30	$0
	SPOREs-P50	$0
	Other P50s/P20s	$0
	Other Specialized Centers	$8,439,608
	Subtotal, Centers	$8,439,608
Other Research–Grants	Cancer Education Program-R25 (including BD2K)	$0
	Education Projects- UE5	$0
	Clinical Cooperative Groups-U10/UG1	$157,267,845
	Pre-Doc Post-Doc Transition Awards-F99	$0
	Minority Biomedical Support-S06	$0
	Research pathway in Residency-R38	$0
	Pilot Research Project-OT2	$0
	Resource Grants-R24/U24/U2C	$0
	Cooperative Conference Agreements-U13/R13	$0
	International Research Training Grants-D43/U2R	$0
	Subtotal, Other Research Grants	$157,267,845
Subtotal, Research Grants		$165,707,453
R&D Contracts	R&D Contracts	$35,475,826
	SBIR Contracts	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, Contracts	$35,475,826
Research Management & Support (RMS)	RMS	$28,867,030
	SBIR RMS	$0
	NIH Management Fund/SSF Assessment	$0
	Subtotal, RMS	$28,867,030
*Total DCP		$230,050,309

Division of Extramural Activities (DEA)

DEA Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Research Management & Support (RMS)	RMS	$19,700,903
	SBIR RMS	$0
	NIH Management Fund/SSF Assessment	$0
	Total DEA	$19,700,903

Office of the Director (OD)

OD Obligations
*(Whole Dollars)*
Type of Mechanism	Mechanism	Amount
Research Project Grants (RPGs)	Non-Competing	$0
	Administrative Supplements	$0
	Competing	$0
	Subtotal, without SBIR/STTR Grants	$0
	SBIR/STTR Grants-R41 -44	$181,570,134
	Subtotal, RPGs	$181,570,134
Centers & SPOREs	Cancer Centers Grants-P20/P30	$346,522,441
	SPOREs	$352,966
	Other P50s/P20s	$333,441
	Other Specialized Centers	$45,211,730
	Subtotal, Centers	$392,420,578
Other Research–Career Program	Career Program	$0
	Post-Doc Fellow Awards-K00	$7,927,586
	Research Scientist Development Award-K01	$5,459,615
	Research Scientist Award-K05	$0
	Academic/Teacher Award-K07	$0
	Clinical Investigator-K08	$52,509,965
	Physician Scientist Award (Program)-K12	$17,127,656
	Transitional Career Development-K22	$8,907,559
	Mentored Patient Oriented RCDA-K23	$0
	Midcareer Investigator Award in Patient-Oriented Research-K24	$0
	Mentored Quantitative Research Career Development Award-K25	$898,485
	Early Stage Mentored Research and Career Development-K38	$313,005
	International Research Career Development Award-K43	$341,457
	Career Transition Award-K99	$13,210,377
	Subtotal, Career Program	$106,695,705
Other Research–Grants	Cancer Education Program-R25 (including BD2K)	$25,863,349
	Education Projects-UE5	$0
	Clinical Cooperative Groups-U10/UG1	$5,214,547
	Pre-Doc Post-Doc Transition Awards-F99	$0
	Minority Biomedical Support-S06	$0
	Research Pathway in Residency-R38	$0
	Pilot Research Project-OT2	$0
	Resource Grants-R24/U24/U2C	$0
	Cooperative Conference Agreements-U13/R13	$0
	International Research Training Grants-D43/U2R	$0
	Subtotal, Other Research–Grants	$31,077,896
Subtotal, Research Grants		$711,764,313
NRSA Fellowships		$78,521,990
R&D Contracts	R&D Contracts	$234,519,625
	SBIR Contracts	$14,212,371
	NIH Management Fund/SSF Assessment	$0
	Subtotal, Contracts	$248,731,996
Intramural Research	Program	$266,800,975
	NIH Management Fund/SSF Assessment	$0
	Subtotal, Intramural Research	$266,800,975
Research Management & Support (RMS)	RMS	$177,123,541
	SBIR RMS	$4,772,653
	NIH Management Fund/SSF Assessment	$0
	Subtotal, RMS	$181,896,194
Buildings and Facilities		$30,000,000
*Total OD		$1,517,715,468