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Specialized Programs of Research Excellence (SPOREs)

In 1992, NCI established the Specialized Programs of Research Excellence (SPORE). The Translational Research Program (TRP) is the home of the SPOREs, a cornerstone of NCI’s efforts to promote collaborative, interdisciplinary translational cancer research. SPORE grants involve both basic and clinical/applied scientists, and support projects that will result in new and diverse approaches to the prevention, early detection, diagnosis, and treatment of human cancers.

Each SPORE focuses on a specific organ site, such as breast or lung cancer, or on a group of highly related cancers, such as gastrointestinal cancers. SPOREs are designed to enable the rapid and efficient movement of basic scientific findings into clinical settings, as well as to determine the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

For more information on organ sites, please visit the Translational Research Program.

The NCI Funded Research Portfolio (NFRP) web site contains additional information about the SPORE grants listed below that have been funded by NCI. The NFRP provides access to various NCI budget reports that contain information about research funding according to specific research categories.

For more detailed information on these SPORE grants, visit the NCI Funded Research Portfolio (NFRP).

Download the Data

Fiscal Year 2023 Funding for SPORE Grants
(Whole Dollars)
Mechanism Site Amount
P50 & P20 SPOREs Brain $13,225,565
Breast $11,143,857
Cervical $1,672,035
Disparities/Breast & Lung $1,673,168
Endometerial  $2,384,742
Epigenetic $4,619,587
Gastrointestinal  $6,855,962
Head and Neck $5,898,494
Hyperactive RAS $2,139,494
Kidney $4,361,627
Leukemia $4,486,023
Liver $3,035,095
Lung $12,815,820
Lymphoma $2,048,062
Multiple Myeloma $4,233,641
Ovarian $9,454,021
Pancreas $6,557,382
Prostate $14,095,451
Radiation $2,066,150
Sarcoma $918,606
Skin $9,849,435
  Total P50 SPOREs $123,534,217
Co-funded Head & Neck $575,000
  Total Co-funded $575,000
Total Number of SPOREs, Total SPORE Funding $124,109,217
Total funding shown represents the SPORE program using relevant co-funded grants external to NCI.
Includes fiscal year 2023 Cancer Moonshot funding and excludes all carryover obligations for fiscal years 2022 through 2018.
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