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Specialized Programs of Research Excellence (SPOREs)

In 1992, NCI established the Specialized Programs of Research Excellence (SPOREs). The Translational Research Program (TRP) is the home of the SPOREs, which are a cornerstone of NCI’s efforts to promote collaborative, interdisciplinary, translational cancer research. SPORE grants involve both basic and clinical/applied scientists. They support projects that may result in new and diverse approaches to the prevention, early detection, diagnosis, and treatment of human cancers. 

Each SPORE focuses on cancers in specific organ sites, such as breast or lung cancer, or on a group of highly related cancers, such as gastrointestinal cancers. SPOREs enable the rapid and efficient movement of basic scientific findings into clinical settings and the determination of the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

For more information on organ sites, please visit the Translational Research Program.

The NCI Funded Research Portfolio (NFRP) web site contains additional information about the SPORE grants listed below which have been funded by NCI. The NFRP provides access to various NCI budget reports that contain information about research funding according to specific research categories.

For more detailed information on these SPORE grants, visit the NCI Funded Research Portfolio (NFRP)

Download the Data

Fiscal Year 2025 Funding for SPORE Grants
(Whole Dollars)
MechanismSiteAmount
P50 & P20 SPOREsBrain$11,426,641
Breast$9,827,686
Cervical$2,261,467
Disparities/Breast & Lung$1,518,911
Disparities: GI$2,455,587
Endometrial $4,984,688
Epigenetic$2,521,916
Gastrointestinal $2,398,107
Head and Neck$5,799,629
Hyperactive RAS$2,300,532
Kidney$3,567,077
Leukemia$4,534,284
Liver$4,800,010
Lung$9,250,003
Lymphoma$3,109,934
Multiple Myeloma$2,224,423
Ovarian$8,513,546
Pancreas$6,947,873
Prostate$17,436,103
Radiation$2,027,150
Sarcoma$6,169,145
Skin$7,540,340
 Total P50 SPOREs$121,615,052
Total SPORE Funding$121,615,052
Total funding shown represents the SPORE program.
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