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Specialized Programs of Research Excellence (SPOREs)

In 1992, the NCI established the Specialized Programs of Research Excellence (SPORE). The Translational Research Program (TRP) is the home of the SPOREs, a cornerstone of NCI’s efforts to promote collaborative, interdisciplinary translational cancer research. SPORE grants involve both basic and clinical/applied scientists, and support projects that will result in new and diverse approaches to the prevention, early detection, diagnosis and treatment of human cancers.

Each SPORE focuses on a specific organ site, such as breast or lung cancer, or on a group of highly related cancers, such as gastrointestinal cancers. SPOREs are designed to enable the rapid and efficient movement of basic scientific findings into clinical settings, as well as to determine the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

For more information on organ sites, please visit the Translational Research Program.

The NCI Funded Research Portfolio (NFRP) web site contains additional information about the SPORE grants listed below that have been funded by NCI. The NFRP provides access to various NCI budget reports that contain information about research funding according to specific research categories.

For more detailed information on these SPORE grants, visit the NCI Funded Research Portfolio (NFRP).

Download the Data

FY 2022 Funding for SPORE Grants
(Whole Dollars)
Mechanism Site Amount
P50 & P20 SPOREs Bladder 2,138,849
Brain 13,372,248
Breast 13,376,020
Cervical 1,869,712
Endometerial & Ovarian 1,002,637
Epigenetic 4,628,214
Gastrointestinal  8,981,248
GI  1,746,186
GI & Lung 1,050,058
Head and Neck 5,461,006
Head and Neck, GI 1,102,970
Kidney 4,321,859
Leukemia 7,053,322
Liver 5,383,018
Lung 12,863,975
Lymphoma 4,442,360
Multiple Myeloma 4,288,814
Ovarian 7,027,898
Pancreas 4,449,663
Prostate 10,110,699
Sarcoma 2,126,450
Skin 10,850,128
  Total P50 SPOREs $127,647,334
Co-funded Head & Neck $575,000
  Total Co-funded $575,000
Total Number of SPOREs, Total SPORE Funding $128,222,334
Total funding shown represents the SPORE program using relevant co-funded grants external to NCI.
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