Specialized Programs of Research Excellence (SPOREs)

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In 1992, the NCI established the Specialized Programs of Research Excellence (SPORE). The NCI Translational Research Program (TRP) is the home of the SPOREs, and a cornerstone of NCI’s efforts to promote collaborative, interdisciplinary translational cancer research. SPORE grants involve both basic and clinical/applied science, and support projects that will result in new and diverse approaches to the prevention, early detection, diagnosis and treatment of human cancers.

Each SPORE focuses on a specific organ site, such as breast or lung cancer, or on a group of highly related cancers, such as gastrointestinal cancers. SPOREs are designed to enable the rapid and efficient movement of basic scientific findings into clinical settings, as well as to determine the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

Download Table Data

FY 2016 Funding for SPORE Grants
(Whole Dollars)
Mechanism Site Number Amount
P50 SPOREs Brain 4 $8,357,798
Breast 6 12,454,145
Cervical 1 2,152,942
Genitourinary 2 4,066,211
Gastrointestinal (GI) 5 8,420,407
Head and Neck 3 5,980,720
Leukemia 2 4,385,801
Lung 3 7,998,326
Lymphoma 3 6,968,336
Melanoma 2 4,323,999
Ovarian 2 3,190,849
Pancreatic 4 9,268,450
Prostate 8 18,085,210
Skin 4 8,167,717
Skin 4 8,167,717
Renal 1 2,162,000
Uterine 1 2,162,000
  Subtotal 51 $108,144,911
U54 SPOREs Hyperactive RAS 1 $2,162,000
Sarcoma 2 2,209,691
Subtotal 3 $4,371,691
Co-funded Head & Neck with NIDCR 0 547,200
  Total Co-funded   $547,200
Total Number of SPOREs, Total SPORE Funding 54 $113,063,802
*Total funding shown represents the SPORE program using relevant U54s.
  • Posted: May 25, 2017