Specialized Programs of Research Excellence (SPOREs)

In 1992, the NCI established the Specialized Programs of Research Excellence (SPORE). The Translational Research Program (TRP) is the home of the SPOREs, a cornerstone of NCI’s efforts to promote collaborative, interdisciplinary translational cancer research. SPORE grants involve both basic and clinical/applied scientists, and support projects that will result in new and diverse approaches to the prevention, early detection, diagnosis and treatment of human cancers.

Each SPORE focuses on a specific organ site, such as breast or lung cancer, or on a group of highly related cancers, such as gastrointestinal cancers. SPOREs are designed to enable the rapid and efficient movement of basic scientific findings into clinical settings, as well as to determine the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

The NCI Funded Research Portfolio (NFRP) web site contains additional information about the SPORE grants listed below that have been funded by NCI. The NFRP provides access to various NCI budget reports that contain information about research funding according to specific research categories.

Download the Data

FY 2017 Funding for SPORE Grants
(Whole Dollars)
Mechanism Site Amount
P50 SPOREs Brain $11,352,070
Breast 9,090,499
Cervical 2,300,000
Endometrial 2,491,997
Gastrointestinal (GI) 5,377,267
Head and Neck 1,943,901
Kidney 4,600,000
Leukemia 6,916,282
Lung 7,168,935
Lymphoma 7,724,234
Myeloma 4,599,999
Neuroendocrine 2,600,000
Ovarian 6,387,813
Pancreatic 6,822,460
Prostate 20,207,916
Skin 7,173,141
Thyroid 4,414,985
  Subtotal $111,171,499
U54 SPOREs Hyperactive RAS $2,271,783
Subtotal $2,271,783
Co-funded Head & Neck $216,200
  Total Co-funded $216,200
Total Number of SPOREs, Total SPORE Funding $113,659,482
Total funding shown represents the SPORE program using relevant U54s and co-funded grants external to NCI.
  • Posted: February 16, 2018