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Specialized Programs of Research Excellence (SPOREs)

In 1992, NCI established the Specialized Programs of Research Excellence (SPOREs). The Translational Research Program (TRP) is the home of the SPOREs, a cornerstone of NCI’s efforts to promote collaborative, interdisciplinary translational cancer research. SPORE grants involve both basic and clinical/applied scientists. They support projects that may result in new and diverse approaches to the prevention, early detection, diagnosis, and treatment of human cancers. 

Each SPORE focuses on a specific organ site, such as breast or lung cancer, or on a group of highly related cancers, such as gastrointestinal cancers. SPOREs enable the rapid and efficient movement of basic scientific findings into clinical settings and determine the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

For more information on organ sites, please visit the Translational Research Program.

The NCI Funded Research Portfolio (NFRP) web site contains additional information about the SPORE grants listed below that have been funded by NCI. The NFRP provides access to various NCI budget reports that contain information about research funding according to specific research categories.

For more detailed information on these SPORE grants, visit the NCI Funded Research Portfolio (NFRP)

Download the Data

Fiscal Year 2024 Funding for SPORE Grants
(Whole Dollars)
MechanismSiteAmount
P50 & P20 SPOREsBladder$896,275
Brain$11,240,582
Breast$11,846,411
Cervical$1,949,494
Disparities/Breast & Lung$1,693,527
Disparities: GI$2,575,782
Endometerial $5,688,927
Epigenetic$2,421,039
Gastrointestinal $896,274
Head and Neck$5,501,419
Hyperactive RAS$2,208,392
Kidney$4,463,070
Leukemia$4,366,789
Liver$2,236,005
Lung$5,553,587
Lymphoma$2,075,728
Multiple Myeloma$2,098,348
Ovarian$8,509,129
Pancreas$6,538,889
Prostate$14,662,305
Radiation$1,946,064
Sarcoma$2,375,406
Skin$6,932,849
 Total P50 SPOREs$108,676,291
Co-fundedHead & Neck$575,000
 Total Co-funded$575,000
Total SPORE Funding$109,251,291
Total funding shown represents the SPORE program using relevant co-funded grants external to NCI.
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