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Mentored Patient-Oriented Research Career Development Award (K23)

The Mentored Patient-Oriented Research Career Development Award (K23) supports clinically trained professionals who have made a commitment to focus on patient-oriented research. NCI K23 provides a protected time to early career stage Clinician-Scientists with clinical duties appointment to develop cancer-focused patient-oriented research career.

Please note:  Effective May 9, 2017, NCI will no longer be participating in K23: PA-16-198.  Please see NOT-CA-17-043 and NOT-CA-17-042.    

Patient-Oriented Research is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator directly interacts with human subjects. This area of research includes:

  1. Mechanisms of human disease
  2. Therapeutic interventions
  3. Clinical trials
  4. The development of new technologies

Studies falling under Exemption 4 for human subjects research are not included in this definition. Individuals conducting mentored research that falls under Exemption 4 should refer to the NCI K08.

For more complete information, reference the Program Announcement and/or contact the program staff.

Applicant Eligibility


At the time of the award, the candidate must be:

  • a citizen of the United States,
  • or a noncitizen national,
  • or must have been lawfully admitted for permanent residence and possess an Alien Registration Receipt Card (1-151 or 1-551) or some other verification of legal admission as a permanent resident.

Citizenship or green card is not needed to apply. Citizenship or green card is needed at the time of award issuance.

Foreign Nationals with Student Visas Not eligible for this award
Degree/Academic Appointment
  • Medical, clinical doctorates with active licensure and clinical duties
  • Ph.D with clinical certification and clinical duties
Effort Level/ Commitment Candidate must commit a minimum of 9 calendar months (75%) of full-time professional effort to the K23 Career Development Award.
Duration of Award 3-5 years; the K23 Award is not renewable


Financial Support

Salary Up to $100K/year + fringe benefits
Research Development Support: Tuition/Fees, Books, Supplies/Equipment, Travel to Meetings, Technical Personnel, Statistical Services Up to $30K/year

F&A Costs/Indirect Costs


Ancillary Personnel Support: Salary for Mentors, Secretarial and Administrative Assistance, etc. Not allowed

How to Apply

For assistance with application submission, please see the Frequently Asked Questions and/or contact eRA Commons Help Desk/ contact Center

Application Receipt Dates and Review Schedule

Receipt Cycle Receipt Date: New Application Receipt Date: Resubmission Application Initial Review Council Review Earliest Possible Start Date*
1 February 12 March 12 June/July September/October December
2 June 12 July 12 October/November January/February April
3 October 12 November 12 February/March May/June July

* Start dates are determined by the availability of NCI funds and may not occur until well after the earliest possible start date.

Applications are due by 5 pm local time.

When a standard submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.

Review and Selection Process

The Center for Scientific Review (CSR) and the National Cancer Institute (NCI) review applications for completeness and for conformance to all eligibility requirements and special provisions and requirements. Incomplete applications will be returned to the applicant without further consideration.

Subcommittee J, convened by the Division of Extramural Activities of the NCI, evaluates applications according to the review criteria listed in the Program Announcement. Before an award is made, the National Cancer Advisory Board (NCAB) conducts a second level of review and ensures that an application meets the broad program needs and priorities of the NCI and the National Cancer Program.

For review criteria for the K23 grant mechanism, see the Review Criteria section of the Program Announcement.

Find an overview of the grant process


NCI Staff Contacts

For additional information regarding policies and/or guidance in preparing an application for the K23 Award, contact:

  • Updated: