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Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients

Administrative supplement requests received in response to NOT-OD-23-031 are intended to ensure continuity of research among recipients of mentored career development (K) awards by providing supplemental research support to help sustain the investigator’s research during a period in which the PD/PI experiences critical life events which have the potential to impact research progress or potential productivity. Administrative supplements must support work within the scope of the original project.

Reference  NOT-OD-23-031 and PA-20-272 for additional information. The information on this website is not intended to replace the detailed information in the program announcement.

Applicant Eligibility

PD/PIs of the following activity codes are eligible for the award: K00, K01, K07, K08, K22, K23, K25, K38, K43, K76, and K99/R00 (on the mentored K99 portion of the K99/R00).

Individual(s) must hold an active grant, and the research proposed in the supplement must typically be accomplished within the competitive segment of the active award. Individuals are encouraged to work with their organizations to develop applications for support.

For the purposes of this program, critical life events that would qualify for consideration include childbirth, adoption, serious personal health issues or illness and/or debilitating conditions, high-risk pregnancy, and primary caregiving responsibilities of an ailing spouse, child, partner, parent or a member of the immediate family during the project. Evidence that the circumstance may affect advancement of the mentored career development award or productivity must be provided. In circumstances in which the critical life event is pending and is expected to occur during the project period, the supplement request may be submitted in advance of the event. Detailed personal health information such as specific diagnoses or medical conditions is not required or necessary to be considered for this supplement.


The administrative supplement budget is limited to 1 year. The application budget cannot exceed a maximum direct cost of $70,000; applicable F&A (indirect) cost can also be requested.

Flexible use of supplemental funds is highly encouraged to support successful research within the scope of the parent project, including supported effort of additional personnel, computational services, supplies and equipment to sustain the research of the PD/PI of the individual K award during a critical life event. Supplement funds may not be used for PI salary support during the regular or extended period of the grant.

Direct Costs up to $70,000
F&A Costs/Indirect Costs 8%
Award Period up to 12 months

How to Apply

Supplement requests must be submitted in accordance with the parent program announcement: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-20-272 or its subsequent reissued equivalent. For funding consideration, applicants must include “NOT-OD-23-031” (without quotation marks) in the Agency Routing Identifier field (box 4b) of the SF424 R&R form. Applications without this information in box 4b will not be considered for this initiative.

Supplement requests should be submitted electronically. The process for Streamlined Submissions using the eRA Commons cannot be used for this initiative.

Applicants must follow the instructions in the SF424 (R&R) Application Guide, as well as any program-specific instructions in NOT-OD-23-031 and PA-20-272.

All page limitations applicable to the parent award as described in the Application Guide and the Table of Page Limits must be followed.

Required Sections

  • Face Page or R&R Cover Form
  • Project/Performance Sites
  • Senior/Key Personnel, Other Significant Contributors
  • PHS 398 budget section
  • Biosketches (NEW key personnel)
  • PHS 398 Career Development Award Supplemental Form 
    • Candidate Information and Goals for Career Development attachment: Personal Statement from the applicant, including long-term research objectives and career goals, a justification for the supplemental support, and a plan to return to full productivity at the end of the supplement period.
    • Institutional Commitment to Candidate’s Research Career Development attachment: Institutional letter of commitment that includes details of resources and mentoring to be made vailable to the applicant to ensure strong productivity on the parent grant. The letter should also detail the institutional commitment to the applicant’s return to full productivity and research career trajectory at the end of the supplement period.
  • PHS 398 Research Plan Form: At a minimum, the Research Strategy section should be completed and must include a summary or abstract of the funded parent award or project. Other sections should also be included if they are being changed by the proposed supplement activities.
  • PHS Human Subjects and Clinical Trial Information: This form is optional. Given that the proposed supplement cannot change the scope of the awarded parent project, it will typically not be needed. If new recruitment or use of an additional existing dataset or resource is proposed in the supplement application, Section 2.4 should be revised and new Inclusion Enrollment Reports created, as appropriate.

NCI-Specific Information

  • NCI accepts supplement applications on a continuous basis. Applications received after July 1st of the current fiscal year will be considered for funding in the following fiscal year.
  • Projects in no-cost extension are not eligible.
  • Only one supplement application may be submitted to this NOSI for each Qualifying Critical Life Event.
  • The Qualifying Critical Life Event must be current or have occurred within the year prior to the supplement application submission.
  • Applicants should provide a strong justification for the need for supplemental support.
  • Administrative reviews and processing can take up to 12 weeks.​


NCI Staff Contacts

For additional information regarding policies and/or guidance in preparing an application for the K-supplement, contact:

  • Updated:

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