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Cancer Currents: An NCI Cancer Research Blog

A blog featuring news and research updates from the National Cancer Institute.

An illustrated banner to represent NCI's Cancer Currents research news blog. The design features interconnected scenes: a patient receiving care, a researcher in a lab, a tumor model, a laptop and mobile device displaying research articles, fitness activity, a clinical setting, and a researcher giving a scientific presentation. The background showcases rolling hills and abstract buildings.
  • A close-up of a mother holding a newborn baby against her chest. The baby has a small hat and is covered with a blanket. The woman’s head rests against a pillow.
    • By Sharon Reynolds

    As adults, survivors of childhood cancer aren’t any less likely to have healthy babies than those without a history of cancer, a new study shows. However, they may have more health risks during pregnancy, warranting more intensive obstetric care.

  • A computer generated image of a nanoparticle micelle. The main section shows clumps of red and yellow against each other, with long light-blue strands emerging from the main cluster.
    • By Nadia Jaber

    A nanoparticle coating may help cancer drugs reach medulloblastoma tumors in the brain and make the treatment less toxic. Mice treated with nanoparticles containing palbociclib (Ibrance) and sapanisertib lived substantially longer than those treated with either drug alone.

  • An infographic titled “Percentage of Women Overdue for Cervical Cancer Screenings.” A left box reads 14% in 2005, and an arrow points to a box on the right that reads 23% in 2019.
    • By Edward Winstead

    The rates of timely cervical cancer screening fell between 2005 and 2019, researchers found, and disparities existed among groups of women. The most common reason for not receiving timely screening was lack of knowledge about screening or not knowing they needed screening.

  • A microscopic image of a regular cell, an infected cell, and a T cell. The T cell contains a cluster of small red-pink dots, which can also be seen moving into the infected cell.
    • By Sharon Reynolds

    Removing immune cells called naive T cells from donated stem cells before they are transplanted may prevent chronic graft-versus-host disease (GVHD) in people with leukemia, a new study reports. The procedure did not appear to increase the likelihood of patients’ cancer returning.

  • Illustration of the anatomy of the biliary tract
    • By Elia Ben-Ari

    Adding durvalumab (Imfinzi) to standard chemotherapy modestly extended how long people with advanced biliary tract cancer lived, results from the TOPAZ-1 trial show. The immunotherapy drug may now be the standard first-line therapy for this hard-to-treat cancer.

  • A flyer in support of smoke-free casinos on Navajo Nation lands
    • By Patricia Nez Henderson, M.D., M.P.H., and Scott Leischow, Ph.D.

    With the passage of the Air is Life Act of 2021, the Navajo Nation enacted the most comprehensive ban on commercial tobacco products of any American Indian tribe to date.

  • Illustration showing progression from normal liver to nonalcoholic steatohepatitis.
    • By NCI Staff

    Researchers have found that mice that lack β2-spectrin protein in their livers are protected from nonalcoholic fatty liver disease and the most common kind of liver cancer, hepatocellular carcinoma.

  • Cover of “Closing Gaps in Cancer Screening: Connecting People, Communities, and Systems to Improve Equity and Access” which also includes the text “A Report to the President of the United States From the President’s Cancer Panel” as well as the President’s Cancer Panel Logo. A collage of images - doctors speaking to patients and medical equipment - merge with shapes and icons, such as hexagons, that evoke a scientific feeling.
    • By John P. Williams, M.D.

    Dr. John P. Williams, chair of the President’s Cancer Panel, summarizes the panel’s new report, Closing Gaps in Cancer Screening: Connecting People, Communities, and Systems to Improve Equity and Access.

  • Illustration of HLA proteins presenting peptides on cell surface.
    • By Nadia Jaber

    A specific form of the HLA gene, HLA-A*03, may make immune checkpoint inhibitors less effective for some people with cancer, according to an NCI-led study. If additional studies confirm the finding, it could help guide the use of these commonly used drugs.

  • Photo of a health insurance statement
    • By Edward Winstead

    Financial hardship caused by cancer care was common and occurred early in treatment, even for patients with insurance, a recent study found. The investigators believe financial hardship should be addressed like any other complication of cancer care.

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