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2020 - Cancer Currents Blog

  • Illustration of a core needle biopsy of the breast.
    • By NCI Staff

    Researchers have developed a “microscaled” approach to analyze the proteins and genetic changes (proteogenomics) of a tumor that uses tissue from a core needle biopsy. The analyses can provide important information that may help guide treatment.

  • Bone scan showing bone loss after chemotherapy
    • By NCI Staff

    Bone loss associated with chemotherapy appears to be induced by cells that stop dividing but do not die, a recent study in mice suggests. The researchers tested drugs that could block signals from these senescent cells and reverse bone loss in mice.

  • A diagram of a CAR T cell highlighting the changed components of the engineered receptor.
    • By NCI Staff

    A remodeled CAR T-cell therapy causes fewer neurologic side effects and is equally effective as the original form of the treatment, according to results from the first clinical trial testing the approach in patients with B-cell lymphomas.

  • A nurse showing an African American man his test results.
    • By NCI Staff

    In the Veterans Affairs health care system—where all patients have equal access to care—African American men did not appear to have more-aggressive prostate cancer when diagnosed or a higher death rate from the disease than non-Hispanic white men.

  • Image of surgical staff reviewing an image of a brain tumor biopsy.
    • By NCI Staff

    A method that combines artificial intelligence with an advanced imaging technology can accurately diagnose brain tumors in fewer than 3 minutes during surgery, a new study shows. The approach can also accurately distinguish tumor from healthy tissue.

  • Scans of the chest after traditional radiation therapy and after proton therapy, which show how much surrounding tissue is affected by each type of therapy.
    • By NCI Staff

    Some experts believe that proton therapy is safer than traditional radiation, but research has been limited. A new observational study compared the safety and effectiveness of proton therapy and traditional radiation in adults with advanced cancer.

  • Kinome trees with circles representing potency of binding for four targeted TKIs.
    • By NCI Staff

    Avapritinib (Ayvakit) has been approved for adults with gastrointestinal stromal tumors (GIST) whose tumors have an alteration in a portion of the PDGFRA gene called exon 18. The approval applies to those whose tumors cannot be removed with surgery or have spread.

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