2023 - Cancer Currents Blog
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Researchers have used a form of CRISPR, called base editing, to engineer T cells and hematopoietic stem cells as part of a potential “universal” CAR T-cell therapy for blood cancers. In experiments in mice, the treatment rapidly eliminated tumors, including in mice with acute myeloid leukemia (AML).
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Engineered bacteria can detect tumor DNA that has been shed into the gut by colorectal tumors, a new study in mice shows. The bacteria are programmed to seek and capture DNA containing a specific genetic change found in cancer.
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Many people being treated for cancer and longer-term cancer survivors reported regularly drinking alcohol—some heavily and often, a new study shows. The study’s leaders said the findings should be “wake-up call” for cancer care providers.
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For women in their 70s and older, the risk of overdiagnosis with routine screening mammography is substantial, a new study suggests. The findings highlight the need for conversations between older women and their health care providers about the potential benefits and harms of continuing screening mammography.
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The cholesterol-lowering drug atorvastatin (Lipitor) may help reduce the risk of heart failure in people with lymphoma who receive chemotherapy drugs called anthracyclines, results from a clinical trial suggest. Anthracyclines, such as doxorubicin, are used to treat many types of cancer.
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It may be worthwhile for some individuals between ages 65 and 69 to get tested for HPV, findings from a Danish study suggest. Specifically, the testing may help prevent cervical cancer among those who haven’t had cervical cancer screening for at least 5 years.