nab-paclitaxel
View Patient InformationA Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with antineoplastic activity. Paclitaxel binds to and stabilizes microtubules, preventing their depolymerization and so inhibiting cellular motility, mitosis, and replication. This formulation solubilizes paclitaxel without the use of the solvent Cremophor, thereby permitting the administration of larger doses of paclitaxel while avoiding the toxic effects associated with Cremophor.
| Synonym: | albumin-bound paclitaxel albumin-stabilized nanoparticle paclitaxel nab paclitaxel nanoparticle albumin-bound paclitaxel nanoparticle paclitaxel paclitaxel albumin paclitaxel protein-bound protein-bound paclitaxel |
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| US brand name: | Abraxane |
| Code name: | ABI 007 ABI-007 |