trastuzumab
View Patient InformationA recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas.
| Synonym: | anti-c-erB-2 anti-c-erbB2 monoclonal antibody anti-ERB-2 anti-erbB-2 anti-erbB2 monoclonal antibody anti-HER2/c-erbB2 monoclonal antibody anti-p185-HER2 c-erb-2 monoclonal antibody Herceptin biosimilar PF-05280014 Herceptin trastuzumab biosimilar PF-05280014 MoAB HER2 monoclonal antibody c-erb-2 monoclonal antibody HER2 trastuzumab biosimilar ABP 980 trastuzumab biosimilar ALT02 trastuzumab biosimilar CT-P6 trastuzumab biosimilar EG12014 trastuzumab biosimilar HLX02 trastuzumab biosimilar PF-05280014 trastuzumab biosimilar PF-05280014 trastuzumab biosimilar QL1701 trastuzumab biosimilar SB3 trastuzumab biosimilar SIBP-01 trastuzumab-anns trastuzumab-dkst trastuzumab-dttb trastuzumab-pkrb trastuzumab-qyyp trastuzumab-strf |
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| US brand name: | Herceptin Hercessi Herzuma Kanjinti Ogivri Ontruzant Trazimera |
| Foreign brand name: | Biceltis CANMab Herclon Hertraz |
| Abbreviation: | MoAB HER2 rhuMAb HER2 |
| Code name: | ABP 980 ALT02 CT-P06 CT-P6 PF-05280014 QL 1701 QL-1701 QL1701 RO0452317 SB3 |
| Chemical structure: | immunoglobulin G 1 (human-mouse monoclonal RhuMab HER2gamma1-chain antihuman p185(Sup c-erbB2) receptor), disulfide with human-mouse monoclonal RhuMab HER2 light chain, dimer |
| NSC code: | 688097 |