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triptorelin pamoate

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The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men.
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Synonym:pamorelin
triptorelin embonate
US brand name:Trelstar
Trelstar Depot
Foreign brand name:Decapeptyl
Diphereline
Chemical structure:6-D-tryptophan-, 4,4'mmethylenebis(3-hydroxy-2-naphthalenecarboxylate) (salt)
NSC code:724666
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