Skip to main content
An official website of the United States government

lurbinectedin

View Patient Information
A synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogue with potential antineoplastic activity. Lurbinectedin covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death.
US brand name:Zepzelca
Code name:PM-01183
PM01183
Search NCI's Drug Dictionary