NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- trastuzumab
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A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym: anti-c-erB-2
anti-c-erbB2 monoclonal antibody
anti-ERB-2
anti-erbB-2
anti-erbB2 monoclonal antibody
anti-HER2/c-erbB2 monoclonal antibody
anti-p185-HER2
Herceptin biosimilar PF-05280014
Herceptin trastuzumab biosimilar PF-05280014
MOAB HER2
monoclonal antibody c-erb-2
monoclonal antibody HER2
trastuzumab biosimilar ABP 980
trastuzumab biosimilar ALT02
trastuzumab biosimilar EG12014
trastuzumab biosimilar HLX02
trastuzumab biosimilar PF-05280014
trastuzumab biosimilar SB3US brand name: Herceptin
Herzuma
OgivriAbbreviation: MOAB HER2
rhuMAb HER2Code name: ABP 980
PF-05280014
RO0452317