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Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

ECM

A large network of proteins and other molecules that surround, support, and give structure to cells and tissues in the body. The ECM helps cells attach to, and communicate with, nearby cells, and plays an important role in cell growth, cell movement, and other cell functions. The ECM is also involved in repairing damaged tissue. Abnormal changes in the ECM may lead to the development of certain diseases, such as cancer. The ECM of cancer cells can affect how they grow and spread. Also called extracellular matrix.
Search NCI's Dictionary of Cancer Terms