This page contains brief information about the drug combination called R-EPOCH. The drugs in the combination are listed, and links to individual drug summaries are included.

Drugs in the R-EPOCH combination:
R = Rituximab
E = Etoposide Phosphate
P = Prednisone
O = Vincristine Sulfate (Oncovin)
C= Cyclophosphamide
H= Doxorubicin Hydrochloride (Hydroxydaunorubicin)

Chemotherapy is often given as a combination of drugs. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

R-EPOCH is used to treat:

This combination may also be used with other drugs or treatments or to treat other types of cancer. It is being studied in the treatment of Hodgkin lymphoma and B-cell acute leukemia.

More About R-EPOCH

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

Research Results and Related Resources

NIH Study Finds Low-Intensity Therapy for Burkitt Lymphoma is Highly Effective

NIH Trial Shows Promising Results in Treating a Lymphoma in Young People

  • Posted: March 5, 2015
  • Updated: August 31, 2016