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This combination contains the chemotherapy drugs etoposide phosphate, vincristine sulfate (Oncovin), cyclophosphamide, and doxorubicin hydrochloride (hydroxydaunomycin), the targeted therapy drug rituximab, and the steroid hormone prednisone. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Drugs in the R-EPOCH combination:
R = Rituximab
E = Etoposide Phosphate
P = Prednisone
O = Vincristine Sulfate (Oncovin)
C= Cyclophosphamide
H= Doxorubicin Hydrochloride (Hydroxydaunorubicin)

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

R-EPOCH is used to treat:

This combination may also be used with other drugs or treatments or to treat other types of cancer. It is being studied in the treatment of Hodgkin lymphoma and B-cell acute leukemia.

More About R-EPOCH

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

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