This page contains brief information about trastuzumab (Herceptin, Ogivri, Herzuma) and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
Use in Cancer
Trastuzumab is approved to be used alone or with other drugs to treat:
- Adenocarcinoma of the stomach or gastroesophageal junction. It is used for HER2 positive (HER2+) disease that has metastasized (spread to other parts of the body) in patients who have not already been treated for metastatic cancer. This use is approved for the Herceptin and Ogivri brands of trastuzumab.
- Breast cancer that is HER2+. It is used in patients with:
- Hormone receptor-negative or high-risk cancer. It is given:
- Metastatic cancer. It is given:
- With paclitaxel as first-line treatment for metastatic disease or
- Alone in patients who have received at least one chemotherapy treatment for metastatic disease.
This use is approved for the Herceptin, Ogivri, and Herzuma brands of trastuzumab.
Trastuzumab is also being studied in the treatment of other types of cancer.
More About Trastuzumab
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Trastuzumab - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Trastuzumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.