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Cancer Currents: An NCI Cancer Research Blog

A blog featuring news and research updates from the National Cancer Institute.

An illustrated banner to represent NCI's Cancer Currents research news blog. The design features interconnected scenes: a patient receiving care, a researcher in a lab, a tumor model, a laptop and mobile device displaying research articles, fitness activity, a clinical setting, and a researcher giving a scientific presentation. The background showcases rolling hills and abstract buildings.
  • A daughter sits next to her mother, who's in a wheelchair
    • By Sharon Reynolds

    In a survey of more than 100 US community cancer clinics, only 16% routinely screened informal caregivers of their patients for distress. In contrast, more than 90% regularly screened patients for distress and provided referrals to supportive care services.

  • An illustration showing multiple radiation beams targeting a tumor in a kidney.
    • By Carmen Phillips

    Stereotactic body radiotherapy was effective in people with localized kidney cancer who weren’t able to have surgery to remove their tumor, a clinical trial has shown. No patients had their cancer start growing or died from cancer over the next 5 years.

  • A CT scan showing a metastatic tumor embedded in a spinal vertabrae
    • By Linda Wang

    Treatment with atezolizumab (Tecentriq) shrank tumors in about 40% of people with alveolar soft part sarcoma, including one complete response, new clinical trial findings show. Some people were later able to stop treatment without the cancer returning.

  • A picture of Adan Reinosa in his garage with a piece of a car engine.
    • By Edward Winstead

    The ENLACE study is the first to use cutting-edge technologies to describe the molecular features of colorectal tumors in Hispanic and Latino people. The study’s goals are to improve treatments and increase Hispanic/Latino engagement in cancer research.

  • Illustration depicting the interaction between a modified oncolytic virus, tumor cells, and cancer-fighting T cells. The virus causes tumor cell rupture and releases TGFβ blockers, which inhibit Treg cells, thereby enhancing the efficacy of T cells in fighting cancer.
    • By Shana Spindler

    A cancer-infecting virus engineered to tamp down a tumor’s ability to suppress the immune system shrank tumors in mice, a new study shows. The modified oncolytic virus worked even better when used along with an immune checkpoint inhibitor.

  • A partial image of a doctor holding a colonoscope near a patient in the endoscopy suite.
    • By Sharon Reynolds

    Using computer-aided detection (CAD) during a colonoscopy doesn’t help doctors find the growths most likely to become colorectal cancer, two studies find. Researchers agreed that CAD, which is aided by artificial intelligence technology, needs further refinement.

  • A cartoon of a robot-like character with a nursing cross on its chest and helmet
    • By Edward Winstead

    Can AI chatbots give people accurate information about cancer and its treatment? The answer appears to be: Not yet. Results from two studies have found that, although AI chatbots can gather cancer information from reputable sources, their responses to questions about treatment and other topics can include errors and omissions.

  • An illustration of AML cells floating among other cells
    • By Carmen Phillips

    Researchers have used a form of CRISPR, called base editing, to engineer T cells and hematopoietic stem cells as part of a potential “universal” CAR T-cell therapy for blood cancers. In experiments in mice, the treatment rapidly eliminated tumors, including in mice with acute myeloid leukemia (AML).

  • An illustration depicting the process by which the biosensor bacteria grab and take up tumor DNA
    • By Elia Ben-Ari

    Engineered bacteria can detect tumor DNA that has been shed into the gut by colorectal tumors, a new study in mice shows. The bacteria are programmed to seek and capture DNA containing a specific genetic change found in cancer.

  • A factoid highlighting that 40% of cancer survivors reported heavy drinking
    • By Carmen Phillips

    Many people being treated for cancer and longer-term cancer survivors reported regularly drinking alcohol—some heavily and often, a new study shows. The study’s leaders said the findings should be “wake-up call” for cancer care providers.

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