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Technology - Cancer Currents Blog

News and commentaries on technology used to conduct cancer research, deliver cancer treatment, improve patient care, and screen for cancer, as well as other topics.

  • Three different colored circles with squiggles inside and an icon of a letter sticking out of the top. The circles are labeled "exosome" and the squiggles are labeled "microRNA"
    • By Nadia Jaber

    In a new study involving nearly 1,000 people, a liquid biopsy accurately detected early- and late-stage pancreatic cancer. When paired with a test for the protein CA19-9, the combination accurately identified 97% of people with early-stage disease.

  • Tumor-infiltrating lymphocyte therapy or TIL
    • By Carmen Phillips

    In an event more than three decades in the making, FDA has approved lifileucel (Amtagvi), the first cancer treatment that uses immune cells called tumor-infiltrating lymphocytes, or TILs.

  • Illustration of a blood vessel emerging from a tumor. The vessel contains floating fragments of DNA from healthy cells and tumors.
    • By Sharon Reynolds

    Results from a new study suggest that the presence of circulating tumor DNA (ctDNA) in blood samples can predict which patients with colorectal cancer should and shouldn’t get chemotherapy after surgery to remove their tumors.

  • Graphic showing effects of priming agent on concentration of ctDNA and cell-free DNA on liquid biopsy.
    • By Carmen Phillips

    Using two different techniques, researchers showed they could temporarily boost ctDNA levels in the blood of mice with tumors. With more ctDNA in collected blood draws, a liquid biopsy could better detect cancer, the research team found.

  • Test tubes with shiny stretches of DNA inside
    • By Edward Winstead

    The Food and Drug Administration (FDA) for the first time has granted marketing authorization for a blood test, the Invitae Common Hereditary Cancers Panel. The test detects inherited genetic changes that increase the risk of developing certain cancers.

  • Illustration depicting the interaction between a modified oncolytic virus, tumor cells, and cancer-fighting T cells. The virus causes tumor cell rupture and releases TGFβ blockers, which inhibit Treg cells, thereby enhancing the efficacy of T cells in fighting cancer.
    • By Shana Spindler

    A cancer-infecting virus engineered to tamp down a tumor’s ability to suppress the immune system shrank tumors in mice, a new study shows. The modified oncolytic virus worked even better when used along with an immune checkpoint inhibitor.

  • A partial image of a doctor holding a colonoscope near a patient in the endoscopy suite.
    • By Sharon Reynolds

    Using computer-aided detection (CAD) during a colonoscopy doesn’t help doctors find the growths most likely to become colorectal cancer, two studies find. Researchers agreed that CAD, which is aided by artificial intelligence technology, needs further refinement.

  • A cartoon of a robot-like character with a nursing cross on its chest and helmet
    • By Edward Winstead

    Can AI chatbots give people accurate information about cancer and its treatment? The answer appears to be: Not yet. Results from two studies have found that, although AI chatbots can gather cancer information from reputable sources, their responses to questions about treatment and other topics can include errors and omissions.

  • An illustration depicting the process by which the biosensor bacteria grab and take up tumor DNA
    • By Elia Ben-Ari

    Engineered bacteria can detect tumor DNA that has been shed into the gut by colorectal tumors, a new study in mice shows. The bacteria are programmed to seek and capture DNA containing a specific genetic change found in cancer.

  • A red bean shape on DNA labeled "cell death gene" with the words ON and an arrow pointing to a dividing cell. Below, Red and green bean shapes with a squiggly line connecting them and labeled "TCIP1". The word ON and an arrow pointing to a dead cell.
    • By Nadia Jaber

    Researchers have created a molecule that, in cancer cells, hooks onto the protein BCL6 at one end and another protein that turns genes on at the other end. The result: self-destruct genes are turned up, causing the cancer cells to die.

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