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Cancer Currents: An NCI Cancer Research Blog

A blog featuring news and research updates from the National Cancer Institute.

An illustrated banner to represent NCI's Cancer Currents research news blog. The design features interconnected scenes: a patient receiving care, a researcher in a lab, a tumor model, a laptop and mobile device displaying research articles, fitness activity, a clinical setting, and a researcher giving a scientific presentation. The background showcases rolling hills and abstract buildings.
  • Photo of an infant lying on an exam table with an adult holding a stethoscope to the baby's chest.
    • By Shana Spindler

    Giving the drug blinatumomab (Blincyto) after standard chemotherapy substantially increased survival for infants with an aggressive form of acute lymphoblastic leukemia (ALL), a recent study showed. If confirmed in larger studies, the treatment may become standard therapy for infants with ALL caused by KMT2A rearrangements.

  • A female doctor points to something on tablet as a male patient listens.
    • By Carmen Phillips

    When it comes to cancer prevention, primary care clinicians play a critical role. But there are many barriers to integrating cancer prevention into primary care. Researchers are trying to better understand those barriers and how best to overcome them.

  • A picture of a street through a neighborhood in rural Ohio.
    • By Nadia Jaber

    In a new study, providing rural women with an interactive video about cancer screening and follow-up calls with patient navigators helped get them up to date on screenings for breast, cervical, and colorectal cancer.

  • A 3-D illustration of anatomy in the lower abdomen of a male showing tumors in the colon and rectum.
    • By Edward Winstead

    A new treatment regimen may help improve the survival of some people with advanced colorectal cancer, according to results from an international clinical trial. The new regimen includes bevacizumab (Avastin) and the combination of trifluridine and tipiracil (Lonsurf).

  • An illustration of a young man undergoing an apheresis procedure for stem cell collection.
    • By Elia Ben-Ari

    In a clinical trial of people with multiple myeloma, giving motixafortide with filgrastim markedly increased the number of stem cells that could be collected. The treatment may allow more people with this cancer to get optimal numbers of stem cells for a transplant.

  • A young pregnant woman undergoing an ultrasound in the doctor's office
    • By Sarah Schmelling

    An NIH-led study called IDENTIFY is analyzing what happens when prenatal blood tests in a pregnant person suggests the person may have cancer. Dr. Diana Bianchi and Amy Turriff talk about their experience with the study thus far.

  • Two tubes of blood with zoom-ins showing DNA fragments.
    • By Nadia Jaber

    Researchers have developed a blood test that, in a preliminary study, accurately detected liver cancer, including in people with early-stage disease. The test uses a new type of technology called fragmentomics to analyze bits of DNA in the blood.

  • A scanning electron micrograph showing chromosomes and ecDNA
    • By Carmen Phillips

    A new study shows for the first time that a circular form of DNA, called ecDNA, is present in precancerous tissue and not just cancer cells. The study also suggested that when ecDNA is present in Barrett’s esophagus, that tissue is almost certain to become cancer.

  • Red skin with blisters on male shoulder and back
    • By Edward Winstead

    People with desmoplastic melanoma, a rare form of skin cancer, are likely to benefit from treatment with a single immunotherapy drug, pembrolizumab (Keytruda), according to new results from a small clinical trial.

  • An illustration showing nirogacestat blocking an enzyme called gamma secretase, which is part of a signaling pathway that drives desmoid tumor growth.
    • By Linda Wang

    In a clinical trial, the drug nirogacestat shrank tumors in 40% of people with desmoid tumors. Treatment with nirogacestat also substantially improved progression-free survival, pain, and physical functioning, compared with patients treated with a placebo.

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