NCI Drug Dictionary

The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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prednisone
Patient Information
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:delta 1-cortisone
Delta(1)-Cortisone
deltacortisone
deltadehydrocortisone
metacortandracin
PRD
Prednisonum
Foreign brand name:Adasone
Cortancyl
Dacortin
DeCortin
Decortisyl
Decorton
Deltacortene
Deltison
Deltra
Econosone
Meprosona-F
Ofisolona
Panafcort
Panasol-S
Paracort
Predeltin
Predicor
Predicorten
Prednicort
Prednidib
Prednilonga
Predniment
Prednitone
Promifen
Servisone
Abbreviation:PRED
Chemical structure:
  • 1, 2-dehydrocortisone
  • 1;2-dehydrocortisone
  • 17,21-dihydroxypregna-1,4-diene-3,11,20-trione