NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,413 terms related to cancer and medicine.

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von Hippel-Lindau disease
(von HIH-pul-LIN-dow dih-ZEEZ)
A rare, inherited disorder that causes tumors and cysts to grow in certain parts of the body, including the brain, spinal cord, eyes, inner ear, adrenal glands, pancreas, kidney, and reproductive tract. The tumors are usually benign (not cancer), but some may be malignant (cancer). Patients with von Hippel-Lindau disease have an increased risk of certain types of cancer, especially kidney cancer and pancreatic cancer. The signs and symptoms of von Hippel-Lindau disease usually do not appear until young adulthood. It is caused by a mutation (change) in the VHL gene. Also called VHL disease, VHL syndrome, and von Hippel-Lindau syndrome.