NCI Dictionary of Cancer Terms

The NCI Dictionary of Cancer Terms features 8,398 terms related to cancer and medicine.

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dacomitinib
(DA-koh-MIH-tih-nib)
A drug used to treat non-small cell lung cancer that has spread to other parts of the body and has not already been treated. It is used in patients whose cancer has certain mutations (changes) in a gene called epidermal growth factor receptor (EGFR). It is also being studied in the treatment of other types of cancer. Dacomitinib blocks certain proteins made by the mutated EGFR gene, which may help keep cancer cells from growing and may kill them. It is a type of tyrosine kinase inhibitor. Also called PF-00299804 and Vizimpro.